Wear of a Total Knee Replacement with Antioxidant UHMWPE and Gradually Varying Sagittal Curvature

+MR Dressler, S Swope, J Tikka, C Hardaker, M Heldreth, T Render +DePuy Orthopaedics Research, Warsaw, IN [email protected] INTRODUCTION An estimated 46 million Americans suffer from osteoarthritis [1]. As tissue engineered treatments and other options remain on the horizon, total knee arthroplasty (TKA) continues to be an efficacious solution for severe osteoarthritis and has been increasingly applied to younger more active patients [2]. Consequently, new TKA devices are emerging that address previous challenges to long term success such as momentary instability, backside wear of modular devices, and oxidation of UHMWPE. The objective of this study was to evaluate the in vitro wear of a knee system with a novel femoral condyle geometry based upon a gradually changing sagittal curvature, refined tibio-femoral articulation, a new tibial insert locking mechanism, and an anti-oxidant containing poly material